Summary: Garden Bio-chemical's scientific
research project of extracting cholesterol from lanolin extends its VD3
industrial chain. In the future, the company will use byproduct
24-dehydrocholesterol to produce 25-hydroxyvitamin D3, which will strengthen
its cost advantages of high value-added VD3.
On 29 May, 2015, the project of efficient
separation of sterol homologue from lanolin and the comprehensive utilization
of byproducts, conducted by Zhejiang Garden Bio-chemical High-tech Co., Ltd.
(Garden Bio-chemical), was granted the first prize of the provincial scientific
and technological award in Zhejiang.
The scientific research project has great
impact on the construction of VD3 industrial chain of Garden Bio-chemical. This
project promotes the industrial production of VD3's raw material NF-grade cholesterol
(purity >95%), so that the deadlock of China's heavy reliance upon import
with regard to this raw materials is broken; besides, its byproduct
24-dehydrocholesterol when is produced from manufacturing VD3 will create
higher economic values. From 2011 to 2014, the company achieved a total of
USD52.28 million (RMB320 million) in sales and USD12.25 million (RMB75 million)
in profit from this project.
24-dehydrocholesterol is very difficult to
segregate as it is mingled with cholesterol and its contents are low in
cholesterol. Garden Bio-chemical made technological breakthroughs in this
respect by employing ionic liquids to segregate 24-dehydrocholesterol.
In the future, 24-dehydrocholesterol will
be used as raw material to produce 25-hydroxyvitamin D3. This technology can
use by-products of NF-grade cholesterol to increase profit. 25-hydroxyvitamin
D3 is a high value-added D3 product, which has a promising market potential. It
is not only can serve as high-efficient feed additive, but also the major raw
material for all kinds of health-care products. It is revealed that the
biological value of 25-hydroxyvitamin D3 is three to five times as high as that
of VD3 and it does not need metabolism through liver. On 1 Feb., 2014,
25-hydroxyvitamin D3 was allowed to be applied in the feed industry in China.
Currently, there are few companies which
can produce 25-hydroxyvitamin D3, so Garden Bio-chemical can make full use of
cost advantages to take up the 25-hydroxyvitamin D3 market in the future, and
further consolidate its presence in the VD field. Only Shandong Haineng
Bioengineering Co., Ltd. has the qualification for the manufacturing of this
product, and its products already hit domestic market in 2014. While, in the
overseas market, only DSM masters the manufacturing technique of
25-hydroxyvitamin D3, whose annual sales is around 200 tonnes. Nevertheless,
DSM employs fermentation method, in which there are technological difficulties
in segregation and extraction.
Actually, Garden Bio-chemical began to pay
close attention to 25-hydroxyvitamin D3 very early. In 2014, the company once
produced 25-hydroxyvitamin D3 through pilot-scale experiment and offered
clients to trial use, receiving active responses. In Oct. 2014, the company
raised funds, through an offering of stock, to construct a 100 t/a feed grade
25-hydroxyvitamin D3, and the progress rate was up to 70% by 2014.
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